Description
Humana Press The Complete Spleen Structure Function and Clinical Disorders 2nd Edition 2001 Hardbound by Anthony J. Bowdler
In this thoroughly revised and updated second edition, a panel of distinguished clinical researchers from around the world takes stock of the wealth of new knowledge about the human spleen and applies it to the pathology and treatment of splenic diseases. This much enriched understanding encompasses the spleen's complex role in immunological defense, the recently defined function of particulate filtration by the spleen, and the structural basis for the functions of the spleen, most particularly the microvasculature around which it is organized. Among the diseases and disorders of the spleen considered in detail are splenomegaly, the consequences and management of hyper- and hyposplenism, and 'dilutional anemia.' Recent advances in splenic surgery are also reviewed, especially those techniques intended to preserve at least partial function while removing the greater part of the organ. I. The Structure and Function of the Spleen.- 1 The Anatomy of the Spleen.- 2 The Microanatomy of the Mammalian Spleen: Mechanisms of Splenic Clearance.- 3 Splenic Microcirculatory Blood Flow and Function with Respect to Red Blood Cells.- 4 The Immune Functions of the Spleen.- 5 The Role of the Spleen in Hemostasis.- II. Characteristics of the Disordered Spleen.- 6 The Pathology of the Spleen.- 7 Splenic Pooling and Survival of Blood Cells.- 8 Dilutional Anemia: Abnormalities of Blood Volume in Disorders of the Spleen.- III. Clinical Aspects of Disorders of the Spleen.- 9 The Clinical Significance of the Spleen.- 10 Hyposplenism.- 11 The Relationship of the Spleen to Infection.- 12 Hemolysis and Thrombocytopenia.- 13 Myeloproliferative Disorders.- 14 The Spleen in Lymphoproliferative Disease.- 15 The Spleen in Sickle Cell Disease.- 16 Imaging of Spleen Disorders.- 17 Surgery of the Spleen.