Progress In Medicinal Chemistry Vol42 2004 Edition at Meripustak

Progress In Medicinal Chemistry Vol42 2004 Edition

Books from same Author: King

Books from same Publisher: Elsevier

Related Category: Author List / Publisher List


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  • General Information  
    Author(s)King
    PublisherElsevier
    ISBN9780444511430
    Pages450
    BindingHardback
    LanguageEnglish
    Publish YearMay 2004

    Description

    Elsevier Progress In Medicinal Chemistry Vol42 2004 Edition by King

    This volume includes information on recent advances in five important areas: an account of inhibitors of the caspase family of proteolytic enzymes that represent a new class of anti-inflammatory and antiapoptotic agents of potential value in rheumatoid arthritis; and a survey of semi-synthetic and totally synthetic antibiotics and anti-HIV agents and their sites of interaction; the development of inhibitors of the intracellular enzyme acyl-CoA: cholesterol O-acyltransferase (ACAT) for the treatment of hypercholesterolemia; a description of recent progress in growth hormone secretagogues, with the focus on strategies to improve oral bioavailability and duration of action; and information on inhibition of the proteolytic enzyme, hepatitis C protease N-3(NS3), (required for vital replication) as one of the most attractive targets for HCV infections.