Description
Springer Multichain Immune Recognition Receptor Signaling From Spatiotemporal Organization to Human Disease 1st Editon 2009 Hardbound by Alexander Sigalov
MIRRs: Structure and Physiological Function.- T-Cell Receptor.- B-Cell Receptor.- Fc Receptors.- Natural Killer Cell Receptors.- Platelet Glycoprotein VI.- MIRR Signaling: Possible Mechanisms and the Techniques to Study and Visualize.- Clustering Models.- Segregation Models.- Kinetic Proofreading Model.- Serial Triggering Model.- Conformational Model.- Permissive Geometry Model.- Signaling Chain Homooligomerization (SCHOOL) Model.- Visualization of Cell-Cell Interaction Contacts-Synapses and Kinapses.- Visualization of Protein Interactions in Living Cells.- MIRR Signaling and Therapy of Immune Disorders.- Immunogenicity in Peptide-Immunotherapy: From Self/Nonself to Similar/Dissimilar Sequences.- Therapeutic Application of Transmembrane T and Natural Killer Cell Receptor Peptides.- Fc Receptor Targeting in the Treatment of Allergy, Autoimmune Diseases and Cancer.- Therapeutic Blockade of T- Cell Antigen Receptor Signal Transduction and Costimulation in Autoimmune Disease.- MHC and MHC-Like Molecules: Structural Perspectives on the Design of Molecular Vaccines.- SCHOOL Model and New Targeting Strategies.- Immune Receptor Signaling, Aging and Autoimmunity.- Viral Pathogenesis, Modulation of Immune Receptor Signaling and Treatment.