Description
DNA Press Micrornas Biology Function & Expression by Neil J. Clarke
Sixteen chapters review the methods and results of characterizing the function of small, noncoding RNA molecules that appear to serve as negative regulators of gene expression in plants and animals. Topics include RNA-induced silencing complex (RISC) biology, virus- encoded microRNAs, involvement in stem cell division, the miRBase database, and computational prediction of microRNA targets. The contributors are a mixture of researchers working for private laboratories, particularly GlaxoSmithKline, and public universities. Distributed by the Independent Publishers Group. Annotation ©2007 Book News, Inc., Portland, OR (booknews.com)_x000D_ _x000D_
Preface; Part I. Introduction to Testlets: 1. Introduction to testing; 2. Traditional true score theory; 3. Item response theory; 4. Testlet response theory: introduction and preview; 5. The origins of testlet response theory: three alternatives; 6. Fitting testlets with polytomous IRT models: the Law School Admissions Test as an example; Part II. Bayesian Testlet Response Theory: Introduction; 7. A brief history and the basic ideas of modern testlet response theory; 8. The 2-PL Bayesian testlet model; 9. The 3-PL Bayesian testlet model; 10. A Bayesian testlet model for a mixture of binary and polytomous data; 11. A Bayesian testlet model with covariates; 12. Testlet nonresponse theory: dealing with missing data; Part III. Applications and Ancillary Topics: Introduction; 13. Using posterior distributions to evaluate passing scores: The PPoP curve; 14. DIF - Differential Testlet Functioning; 15. Estimation: a Bayesian primer._x000D_