Melanoma Biologically Targeted Therapeutics 1st Editon 2012 Softbound at Meripustak

Melanoma Biologically Targeted Therapeutics 1st Editon 2012 Softbound

Books from same Author: Ernest C. Borden

Books from same Publisher: Humana Press

Related Category: Author List / Publisher List


  • Retail Price: ₹ 7215/- [ 15.00% off ]

    Seller Price: ₹ 6133

Sold By: Book Upload      Click for Bulk Order

Offer 1: Get ₹ 111 extra discount on minimum ₹ 500 [Use Code: Bharat]

Offer 2: Get 15.00 % + Flat ₹ 100 discount on shopping of ₹ 1500 [Use Code: IND100]

Offer 3: Get 15.00 % + Flat ₹ 300 discount on shopping of ₹ 5000 [Use Code: MPSTK300]

Free Shipping (for orders above ₹ 499) *T&C apply.

In Stock

Free Shipping Available



Click for International Orders
  • Provide Fastest Delivery

  • 100% Original Guaranteed
  • General Information  
    Author(s)Ernest C. Borden
    PublisherHumana Press
    Edition1st Edition
    ISBN9781468496680
    Pages388
    BindingSoftbound
    LanguageEnglish
    Publish YearAugust 2012

    Description

    Humana Press Melanoma Biologically Targeted Therapeutics 1st Editon 2012 Softbound by Ernest C. Borden

    Strategies of treatment involving therapeutic proteins, irnrnune immune cells, or cel­ lular protein targets are those of greatest potential for further reducing mortality from melanoma. Therapeutic proteins or cells may inhibit melanoma cell growth either by augmentation of immune cell function or by inhibition of angiogenesis. Cytokines and melanoma antigens may be used either in vivo as a vaccine to stimulate irnrnune immune cell cell function or ex vivo to stimulate or proliferate cells for infusion. Alternatively, alteration in melanoma cell growth can occur through inhibition of protein signal transduction pathways within melanoma cells or in the endothelial cells constituting the necessary angiogenic support for tumor growth. The great promise of these therapies and their cellular targets constitutes the basis for Melanoma: Biologically Targeted Therapeutics. THE CLINlCAL PROBLEM More than four million people will be diagnosed with melanoma in the first decade of the 21st century. Half of those who will die will be individuals who would otherwise have had a life expectancy of another 25 years or more. These individuals will die of systemic systernic metastases, which are present at the time of primary surgery. Despite use of sunscreens, incidence continues to increase in developed countries worldwide. To reduce mortality, there must continue to be a focus on prevention and earlier detection through public education. Early interventions are always preferable to treatment of disseminated metastatic disease. I Perspective on the Clinical Disease.- 1 Management of Primary Malignant Melanoma.- 2 A Pathologist’s Perspective on Prognostic Featuresof Malignant Melanoma.- 3 Clinical Prognostic Factors and Staging.- II Biological and Targeted Therapeutics.- 4 Principles of Antitumor Immunity and Tumor-Mediated Immunosuppression.- 5 Immunotherapy of Advanced Melanoma Directed at Specific Antigens.- 6 Melanoma Antigens: Vaccines and Monoclonal Antibodies.- 7 Interleukin-2.- 8 Interleukin-12: Immunologic and Antitumor Effects in Human Malignant Melanoma.- 9 Interferons: Preclinical and Clinical Studies in Melanoma.- 10 Biochemotherapy of Melanoma.- 11 Signal Transduction Abnormalities as Therapeutic Targets.- 12 Tumor Angiogenesis.- 13 Antiangiogenic Therapy for Melanoma.