Description
Springer M-Health by Robert Istepanian
M-health can be defined as the 'emerging mobile communications and network technologies for healthcare systems.' This book paves the path toward understanding the future of m-health technologies and services and also introducing the impact of mobility on existing e-health and commercial telemedical systems. M-Health: Emerging Mobile Health Systems presents a new and forward-looking source of information that explores the present and future trends in the applications of current and emerging wireless communication and network technologies for different healthcare scenaria. It also provides a discovery path on the synergies between the 2.5G and 3G systems and other relevant computing and information technologies and how they prescribe the way for the next generation of m-health services. The book contains 47 chapters, arranged in five thematic sections: Introduction to Mobile M-health Systems, Smart Mobile Applications for Health Professionals, Signal, Image, and Video Compression for M-health Applications, Emergency Health Care Systems and Services, Echography Systems and Services, and Remote and Home Monitoring. This book is intended for all those working in the field of information technologies in biomedicine, as well as for people working in future applications of wireless communications and wireless telemedical systems. It provides different levels of material to researchers, computing engineers, and medical practitioners interested in emerging e-health systems. This book will be a useful reference for all the readers in this important and growing field of research, and will contribute to the roadmap of future m-health systems and improve the development of effective healthcare delivery systems. FOREWORD Chapter 1. DT40 GENE DISRUPTIONS: A HOW-TO FOR THE DESIGN AND THE CONSTRUCTION OF TARGETING VECTORS Hiroshi Arakawa and Jean-Marie Buerstedde CHAPTER 2. IMMUNOGLOBULIN GENE CONVERSION or HYPERMUTATION: That's the question Jean-Marie Buerstedde and Hiroshi Arakawa CHAPTER 3. Genome resources for the dt40 community Randolph B Caldwell and Andrzej M. Kierzek CHAPTER 4. Chromosome engineering in DT40 cells and mammalian centromere function William RA Brown1, Margaret CM Smith2, Felix Dafhnis-Calas, Sunir Malla and Zhengyao Xu. CHAPTER 5. FUNCTION OF RECQ FAMILY HELICASE IN GENOME STABILITY Masayuki Seki, Shusuke Tada and Takemi Enomoto chapter 6. Genetic analysis of apoptotic execution Sandrine Ruchaud, Kumiko Samejima, Damien Hudson, Scott H. Kaufmann and William C. Earnshaw CHAPTER 7. The DT40 system as a tool for analyzing kinetochore assembly Masahiro Okada, Tesuya Hori and Tatsuo Fukagawa CHAPTER 8. Analysing the DNA damage and Replication Checkpoints in DT40 cells Michael D Rainey, George Zachos, and David AF Gillespie CHAPTER 9. USING DT40 TO STUDY CLATHRIN FUNCTION Frank R. Wettey and Antony P. Jackson CHAPTER 10. GENETIC ANALYSIS OF B CELL SIGNALING Hisaaki Shinohara and Tomohiro Kurosaki CHAPTER 11. DT40 MUTANTS: A MODEL TO STUDY transcriptional regulation of B CELL DEVELOPMENT AND FUNCTION Jukka Alinikula, Olli Lassila and Kalle-Pekka Nera CHAPTER 12. TRANSCRIPTION AND RNA PROCESSING FACTORS PLAY COMPLEX TOLES IN DT40 CELLS Stephanie Bush and James L. Manley CHAPTER 13. PARTICIPATION OF HISTONES, HISTONE MODIFYING ENZYMES AND HISTONE CHAPERONES IN VERTEBRATE CELL FUNCTIONS Hidehiko Kikuchi, Hirak Kumar Barman, Masami Nakayama, Yasunari Takami and Tatsuo Nakayama CHAPTER 14. ANALYSIS OF GENE EXPRESSION, COPY NUMBER AND PALINDROME FORMATION WITH A DT40 ENRICHED cDNA Microarray Paul E. Neima1, Joan Burnside, Katrina Elsaesser, Harry Hwang, Bruce E. Clurman, Robert Kimmel and Jeff DelrowcHAPTER 15. Analysis of DNA replication damage bypass and its role in immunoglobulin repertoire development Julian E. Sale, Anna-Laura Ross and Laura J. Simpson CHAPTER 16. THE FANCONI ANEMIA PATHWAY PROMOTES HOMOLOGOUS RECOMBINATION REPAIR IN DT40 CELL LINE Julian E. Sale, Anna-Laura Ross and Laura J. Simpson CHAPTER 17. CALCIUM SIGNALING, ION CHANNELS AND MORE Anne-Laure Perraud, Carsten Schmitz, Andrew M. Scharenberg CHAPTER 18. Phenotypic analysis of Cellular responses to DNA damage Helfrid Hochegger and Shunichu Takeda CHAPTER 19. ATM, A PARADIGM FOR A STRESS-RESPONSIVE SIGNAL TRANSDUCER IN HIGHER VERTEBRATE CELLS Ken-ichi Yamamoto, Masahiko Kobayashi and Hiroko Shimizu METHOD 1. Stable transfection of DT40 Julian E. Sale METHOD 2. BASIC CELL CULTURE CONDITIONS Huseyin Saribasak and Hiroshi Arakawa METHOD 3. EXCISION OF FLOXED-DNA SEQUENCES BY TRANSIENT INDUCTION OF MER-CRE-MER Hiroshi Arakawa METHOD 4. IMMUNOGLOBULIN GENE CONVERSION AND HYPERMUTATION ASSAY BY FACS Hiroshi Arakawa METHOD 5. TARGET SCREENING BY PCR Hiroshi Arakawa METHOD 6. MITOTIC INDEX DETERMINATION BY FLOW CYTOMETRY David AF Gillespie and Mark Walker METHOD 7. Centrifugal elutriation as a means of cell cycle phase separation and synchronisation David AF Gillespie and Catarina Henriques METHOD 8. preparation of genomic dna for microarray-based comparative genome hybridization Robert Kimmel, Amalia Icreverzi, Paul Neiman METHOD 9. Analysis of cellular Mg2+ in DT40 cells Anne-Laure Perraud, Carsten Schmitz, Andrew M. Scharenberg METHOD 10. Transient transf