Description
Springer Highlights in Asthmology 1st Editon 2011 Softbound by F.B. Michel, J. Bousquet, P. Godard
F. B. Michel Asthmology is the neologism I suggested for ideas which were acceptable at the begin the title of a book published in 1981 on ning of the 20th century, and in particular bronchial asthma [4,5]. to Pasteur's concept of 'one cause, one ill ness', many syndromes like high blood Among a certain number of scientific pressure or asthma are the result of the publications on this subject, it is one of the overlapping of hereditary factors and ac few suggestions that I have the weakness to quired factors. This is one reason why asth feel somewhat proud of. In fact, this word has had the career I hoped it would and, ma is not really an illness in the real sense judging by the frequency with which it is of the word but, a clinical and functional respiratory syndrome [1]. used in both written and spoken language, it did answer a need. I had no intention of The innate, the 'terrain', transmitted by suggesting one more neologism but it heredity, can possibly concern two factors: seemed to me that the word asthmology The bronchial hyperreactivity factor (BHR), had an element of novelty and, above all, is often present in early childhood and its produced the necessary awareness of the reality is a result of the studies of large need to bring together, within a kind of groups of homo- and heterozygotic twins. A. Introduction.- 1. Preface.- 2. Natural History of Asthma.- B. Epidemiology.- 3. Epidemiology of Bronchial Asthma.- 4. Genetic Factors of Allergy.- 5. Changing Prevalence of Asthma in Developing Countries.- C. Etiology.- 6. Viruses.- 7. Allergic Bronchopulmonary Aspergillosis.- 8. Bacterial Asthma.- 9. Exercise-induced Asthma: Clinical Aspects.- 10. Asthma and Gastroesophageal Reflux.- D. Immunology.- 11. The IgE Receptors (Introduction).- 12. Immunological Mechanisms.- 13. Mechanisms of IgE-mediated Immediate Reactions.- 14. Properties of Short-term Sensitizing IgG Antibodies (IgG S-TS) in Asthma.- 15. The Role of Lymphocytes and of their Abnormalities in Atopic Diseases.- 16. Delayed-type Hypersensitivity Responses to Inhalant Allergens: a Form of Cutaneous Basophil Hypersensitivity (CBH).- E. Mediator Release and Bronchial Obstruction.- 17. Physiological and Pharmacological Control of Inflammatory Mediator Release in Bronchial Asthma.- 18. Mast Cells and Basophils.- 19. Alveolar Macrophages.- 20. Neutrophils and the Asthmatic Response.- 21. Eosinophils in Bronchial Asthma.- 22. Mediators of Asthma Derived from Arachidonic Acid.- 23. PAF-acether (Platelet Activating Factor).- 24. Immediate-type Reactions.- 25. Late Phase Reactions.- F. Bronchial Pathophysiology.- 26. Bronchi of Asthmatic Patients.- 27. The Site of Bronchial Obstruction in Asthma.- 28. Factors in Bronchial Hyperreactivity.- 29. Bronchial Hyperreactivity: Autonomie Nervous System Abnormalities.- 30. Bronchial Hyperresponsiveness and Asthma: Unanswered Questions.- G. Asthma due to Allergy Occupation, Food and Drugs.- 31. Preparation and Stability of Pollen Extracts.- 32. Allergen Standardization.- 33. Allergen Avoidance.- 34. Allergens Inducing Asthma (Introduction).- 35. Agricultural Asthma.- 36. Investigation of Occupational Asthma due to Low Molecular Weight Agents.- 37. Occupational Asthma.- 38. Food-related Asthma.- 39. Drug-induced Asthma.- H. Clinical Features and Diagnosis in Children and Adults.- 40. Clinical Aspects of Asthma.- 41. Asthma in Childhood.- 42. Diagnosis of Asthma in Childhood.- 43. Treatment of Childhood Asthma.- 44. Asthma in Adults.- 45. Skin Tests.- 46. Diagnostic Value of IgE in Bronchial Asthma.- 47. Pulmonary Function Tests in Asthma.- 48. Bronchial Provocation Tests.- 49. Status Asthmaticus.- I. Therapeutic Considerations.- 50. Physiopathological Data for the Treatment of Bronchial Asthma.- 51. Possible Therapeutic Developments.