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Drug Metabolism And Transport at Meripustak

Drug Metabolism And Transport

Books from same Author: Lawrence H. Lash

Books from same Publisher: Humana Press Inc.

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    • General Information  
    Author(s)Lawrence H. Lash
    PublisherHumana Press Inc.
    Edition2005 ed.
    ISBN9781588293244
    Pages388
    BindingHardback
    LanguageEnglish
    Publish YearNovember 2004

    Description

    Humana Press Inc. Drug Metabolism And Transport by Lawrence H. Lash

    A compendium of proven experimental approaches and strategies for studying the bioactivation detoxification tissue distribution and elimination of xenobiotics in the metabolism and/or transport of various chemicals. The authors address several of the major drug metabolizing systems including the cytochrome P450 family flavin-containing monooxygenases glutathione S-transferase glucuronidation N-acetylation and sulfotransferases. Additional chapters present novel approaches to the study of: signaling pathways in the regulation of drug metabolism enzymes how the modulation of thiols and other low molecular-weight cofactors can alter drug metabolism and how modulation of drug metabolism pathways can influence antiviral therapy.