Bioprocessing of Viral Vaccines 1st Edition 2022 Hardbound at Meripustak

Bioprocessing of Viral Vaccines 1st Edition 2022 Hardbound

Books from same Author: Kamen, Amine

Books from same Publisher: Taylor and Francis Ltd

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  • General Information  
    Author(s)Kamen, Amine
    PublisherTaylor and Francis Ltd
    Edition1st Edition
    ISBN9781032132112
    Pages320
    BindingHardbound
    LanguageEnglish
    Publish YearSeptember 2022

    Description

    Taylor and Francis Ltd Bioprocessing of Viral Vaccines 1st Edition 2022 Hardbound by Kamen, Amine

    This book focuses on cell culture-produced viral vaccines to meet the needs of the rapidly expanding research and development in academia and industry in the field. This book introduces the basic principles of vaccination and the manufacturing of viral vaccines. Bioprocessing of Viral Vaccines, will provide an overview of the advanced strategies needed to respond to the challenges of new and established viral infection diseases. The first few chapters cover the basics of virology and immunology as essential concepts to understand the function and design of viral vaccines. The core of the content is dedicated to process development, including upstream processing and cell culture of viral vaccines, downstream processing, and extensive analytical technologies specific to viral vaccines. Advanced process analytical technologies (PAT) and Quality by Design (QbD) concepts are also introduced in the context of vaccine manufacturing. The case studies included cover inactivated, attenuated vaccines exemplified by influenza vaccines, sub-unit vaccines exemplified by Virus Like Particles (VLPs: HPV vaccines) and sub-unit vaccines (Flublock), vectored vaccines: adenoviruses and Vesicular stomatitis Virus (VSV) vectored vaccines, genomic vaccines (DNA and mRNA) vaccines as developed for COVID-19 response in particular and a review of COVID-19 vaccines approved or in advanced clinical trials. This book is aimed at graduate engineers and professionals in the fields of vaccinology, bioprocessing, and biomanufacturing of viral vaccines._x000D_ _x000D_ 1. Bioprocessing of viral vaccines-Introduction. 2. Introduction to Virology. 3. Principles of immunology. 4. Cell lines for vaccine production. 5. Upstream Processing for Viral Vaccines - General Aspects. 6. Upstream Processing for Viral Vaccines - Process Intensification. 7. Downstream Processing of Viral Vaccines. 8. Analytical, QbD and PAT Applied to Viral Production Processes. 9. Manufacturing of seasonal and pandemic influenza vaccines - a case study. 10. Recombinant vaccines: Gag-based VLPs. 11. Vectored Vaccines. 12. Design and Production of Vaccines Against COVID-19 using Established Vaccine Platforms._x000D_